<![CDATA[An interesting article on the challenge of bringing new antibiotics to market, and some tactics being used to solve that problem: https://press.asimov.com/articles/antibiotics-failure]]>An interesting article on the challenge of bringing new antibiotics to market, and some tactics being used to solve that problem: https://press.asimov.com/articles/antibiotics-failure

]]>https://postcall.pub/topic/d41df5df-264c-4d71-8fb3-5215a49f101a/an-interesting-article-on-the-challenge-of-bringing-new-antibiotics-to-market-and-some-tactics-being-used-to-solve-that-problem-https-press.asimov.com-articles-antibiotics-failureRSS for NodeMon, 25 May 2026 01:36:39 GMTSun, 03 May 2026 20:24:20 GMT60<![CDATA[Reply to An interesting article on the challenge of bringing new antibiotics to market, and some tactics being used to solve that problem: https://press.asimov.com/articles/antibiotics-failure on Mon, 04 May 2026 00:14:48 GMT]]>@sjslocombe I agree; once we've gotten into a groove, we often stick to it. Doctors are not often in an exploratory mood when they have patients to treat, and having their options suddenly limited due to one thing or another (e.g. patient's sensitivities) is surely disruptive. I feel bad that they make it seem like it's your fault, but it definitely isn't. I hope what you've now gotten works well for you.

]]>https://postcall.pub/post/https://mathstodon.xyz/users/tpfto/statuses/116513419313521358https://postcall.pub/post/https://mathstodon.xyz/users/tpfto/statuses/116513419313521358Mon, 04 May 2026 00:14:48 GMT<![CDATA[Reply to An interesting article on the challenge of bringing new antibiotics to market, and some tactics being used to solve that problem: https://press.asimov.com/articles/antibiotics-failure on Sun, 03 May 2026 23:04:39 GMT]]>@tpfto

A singleton group isn't actually a problem for the purpose of avoiding those 2 classes.

I knew some would be deprecated - the article mentions colistin falling out of favor due to kidney damage and neurotoxicity, for example. And some are only used for this or that; that was in the article, too.

I also know many doctors are lazy and use the same few things over and over again and forget about the other things. Just like everyone else. We cook using the same few ingredients; we use the same few softwares; we choose from the same few brands of car when we're ready to buy; and generally forget all the others exist. And I get very angry at doctors' lack of awareness being framed as my moral failing.

The remaining number might not be 36, but it must be more than 3, because I've been prescribed more than 1 kind of antibiotic.

]]>https://postcall.pub/post/https://mathstodon.xyz/users/sjslocombe/statuses/116513143503985457https://postcall.pub/post/https://mathstodon.xyz/users/sjslocombe/statuses/116513143503985457Sun, 03 May 2026 23:04:39 GMT<![CDATA[Reply to An interesting article on the challenge of bringing new antibiotics to market, and some tactics being used to solve that problem: https://press.asimov.com/articles/antibiotics-failure on Sun, 03 May 2026 21:05:52 GMT]]>@sjslocombe upon reading that, my immediate thought was that "38 is a little exaggerated"; looking at the accompanying infographic showing off those 38, I was right. For instance, nobody really uses arsenic anymore to treat bacterial infections, so the first class depicted in the infographic isn't really a thing anymore. Otherwise, most of those groups depicted are actually singletons: a group with only a single member, because they are chemically and mechanistically unique. Also, some of those groups are specialized, like the ones that are only ever used for treating tuberculosis, or those used for external use only. So, you actually have much less choice because of your allergy; I share your doctor's concern.

]]>https://postcall.pub/post/https://mathstodon.xyz/users/tpfto/statuses/116512676424153887https://postcall.pub/post/https://mathstodon.xyz/users/tpfto/statuses/116512676424153887Sun, 03 May 2026 21:05:52 GMT<![CDATA[Reply to An interesting article on the challenge of bringing new antibiotics to market, and some tactics being used to solve that problem: https://press.asimov.com/articles/antibiotics-failure on Sun, 03 May 2026 20:26:21 GMT]]>It also observes that there are currently 38 classes of antibiotic.

I'm allergic to 2 of those. Once, a doctor said to me that I'd better hope that I don't become allergic to another, because then there'd be nothing left. Now, if I ever hear that again, at least I can point out that there will be 35 classes left. 🙄

]]>https://postcall.pub/post/https://mathstodon.xyz/users/sjslocombe/statuses/116512520995880604https://postcall.pub/post/https://mathstodon.xyz/users/sjslocombe/statuses/116512520995880604Sun, 03 May 2026 20:26:21 GMT