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  3. GLP-1s have proven to me that the vast majority of overweight people are that way because a key part of their endocrine system was damaged by a viral infection - likely a variant of adenovirus that has been plaguing humanity since the late 70s.

GLP-1s have proven to me that the vast majority of overweight people are that way because a key part of their endocrine system was damaged by a viral infection - likely a variant of adenovirus that has been plaguing humanity since the late 70s.

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  • JohnJ John

    Adenovirus-36, to be specific. Although as studies have progressed, apparently several Adenovirus variants are shown to cause obesity regardless of diet in animal subjects.

    https://www.nature.com/articles/s41366-021-00805-6

    3/

    JohnJ This user is from outside of this forum
    JohnJ This user is from outside of this forum
    John
    wrote last edited by
    #4

    GLP-1s are ghrelin agonists: they mimic the impact of the upstream hormone that is a key regulator of metabolism and food intake and processing.

    Taking them doesn't just "slow down digestion", like doctors say. It *transforms* your relationship to food, its effect on your body, and *what* you eat.

    Endocrine shit is wild because it's a system in the body that traverses all other systems. Hormones are skeleton keys to the doors that normally keep each process in its lane.

    4/

    JohnJ 1 Reply Last reply
    0
    • JohnJ John

      GLP-1s are ghrelin agonists: they mimic the impact of the upstream hormone that is a key regulator of metabolism and food intake and processing.

      Taking them doesn't just "slow down digestion", like doctors say. It *transforms* your relationship to food, its effect on your body, and *what* you eat.

      Endocrine shit is wild because it's a system in the body that traverses all other systems. Hormones are skeleton keys to the doors that normally keep each process in its lane.

      4/

      JohnJ This user is from outside of this forum
      JohnJ This user is from outside of this forum
      John
      wrote last edited by
      #5

      Try to remember that metabolism is literally the whole point of the entire fucking body.

      Lungs? Metabolism.

      Vascular system? Heart? Metabolism.

      Entire gut? Metabolism?

      Kidneys, liver, pancreas, spleen? Metabolism.

      Muscles? Exist so we can move to get food to do...metabolism.

      Your esophagus and trachea are just metabolism tubes.

      We are metabolism machines with gonads and nervous systems.

      So no, GLP-1s don't just "slow down digestion" lol lmao

      5/

      JohnJ 1 Reply Last reply
      0
      • JohnJ John

        Try to remember that metabolism is literally the whole point of the entire fucking body.

        Lungs? Metabolism.

        Vascular system? Heart? Metabolism.

        Entire gut? Metabolism?

        Kidneys, liver, pancreas, spleen? Metabolism.

        Muscles? Exist so we can move to get food to do...metabolism.

        Your esophagus and trachea are just metabolism tubes.

        We are metabolism machines with gonads and nervous systems.

        So no, GLP-1s don't just "slow down digestion" lol lmao

        5/

        JohnJ This user is from outside of this forum
        JohnJ This user is from outside of this forum
        John
        wrote last edited by
        #6

        The whole point of this thread is that the last 50 years were caused by a quiet pandemic.

        The popularity of hyper-processed foods? Caused by a quiet pandemic: GLP-1s make them taste gross AF.

        The surge in insulin-related disorders? Caused by a quiet pandemic: GLP-1s regulate insulin with a steel fist.

        The huge increase in people carrying more fat, earlier in life?
        Caused by a quiet pandemic: GIS agonists in some GLP medications correct a strengthening of the body's "starvation" response

        6/

        JohnJ 1 Reply Last reply
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        • JohnJ John

          The whole point of this thread is that the last 50 years were caused by a quiet pandemic.

          The popularity of hyper-processed foods? Caused by a quiet pandemic: GLP-1s make them taste gross AF.

          The surge in insulin-related disorders? Caused by a quiet pandemic: GLP-1s regulate insulin with a steel fist.

          The huge increase in people carrying more fat, earlier in life?
          Caused by a quiet pandemic: GIS agonists in some GLP medications correct a strengthening of the body's "starvation" response

          6/

          JohnJ This user is from outside of this forum
          JohnJ This user is from outside of this forum
          John
          wrote last edited by
          #7

          Not only did the virus make people hungry *all the time*, it made their hunger impossible to dispel.

          Not only did it make their body process food improperly, leading to GI illness and microbiome destruction, it fucked with insulin so they packed on weight while eating less food.

          Not only did it promote fat growth, it *made it much harder to reduce fat*, making weight loss extremely difficult.

          The infection added a ratchet to your body that loves to add fat but hates to burn it off.

          7/

          TaelT JohnJ 2 Replies Last reply
          0
          • JohnJ John

            Not only did the virus make people hungry *all the time*, it made their hunger impossible to dispel.

            Not only did it make their body process food improperly, leading to GI illness and microbiome destruction, it fucked with insulin so they packed on weight while eating less food.

            Not only did it promote fat growth, it *made it much harder to reduce fat*, making weight loss extremely difficult.

            The infection added a ratchet to your body that loves to add fat but hates to burn it off.

            7/

            TaelT This user is from outside of this forum
            TaelT This user is from outside of this forum
            Tael
            wrote last edited by
            #8

            @johnzajac Interesting, this is my first introduction to the idea of infectobesity. Maybe I should get tested for AD-36 antibodies.

            JohnJ 1 Reply Last reply
            0
            • JohnJ John

              Not only did the virus make people hungry *all the time*, it made their hunger impossible to dispel.

              Not only did it make their body process food improperly, leading to GI illness and microbiome destruction, it fucked with insulin so they packed on weight while eating less food.

              Not only did it promote fat growth, it *made it much harder to reduce fat*, making weight loss extremely difficult.

              The infection added a ratchet to your body that loves to add fat but hates to burn it off.

              7/

              JohnJ This user is from outside of this forum
              JohnJ This user is from outside of this forum
              John
              wrote last edited by
              #9

              Accepting that my struggle with weight since adolescence had as much to do with viral post-sequelae as it did with anything else was actually more difficult than I thought it would be. But it helps that before I even tried GLP-1s I had come to terms with myself and my body; I can't imagine dealing with the mental and physical effects of this medication without that peace of mind.

              8/

              JohnJ 1 Reply Last reply
              0
              • TaelT Tael

                @johnzajac Interesting, this is my first introduction to the idea of infectobesity. Maybe I should get tested for AD-36 antibodies.

                JohnJ This user is from outside of this forum
                JohnJ This user is from outside of this forum
                John
                wrote last edited by
                #10

                @tael

                I'm just an opera singer, but I'm not sure antibodies will show up. I think the virus does a real number on the internal mechanisms of cells themselves, perhaps even genetically, a lot like SARS2/COVID does to the immune system.

                We're at the limits of my knowledge lol lmao

                TaelT 1 Reply Last reply
                0
                • JohnJ John

                  Accepting that my struggle with weight since adolescence had as much to do with viral post-sequelae as it did with anything else was actually more difficult than I thought it would be. But it helps that before I even tried GLP-1s I had come to terms with myself and my body; I can't imagine dealing with the mental and physical effects of this medication without that peace of mind.

                  8/

                  JohnJ This user is from outside of this forum
                  JohnJ This user is from outside of this forum
                  John
                  wrote last edited by
                  #11

                  Try to imagine what widespread, constant reinfection with SARS2 is doing to untold systems in the body that will result in "quiet epidemics" of things like the obesity crisis.

                  This is why novid is the only really reasonable choice.

                  Yes, this thread is also about the ongoing COVID pandemic and the long-term consequences of Joe Biden's cynical betrayal of humanity for political gain.

                  9/fin

                  1 Reply Last reply
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                  • JohnJ John

                    @tael

                    I'm just an opera singer, but I'm not sure antibodies will show up. I think the virus does a real number on the internal mechanisms of cells themselves, perhaps even genetically, a lot like SARS2/COVID does to the immune system.

                    We're at the limits of my knowledge lol lmao

                    TaelT This user is from outside of this forum
                    TaelT This user is from outside of this forum
                    Tael
                    wrote last edited by
                    #12

                    @johnzajac That's just what I read on Wikipedia. Is there a particular study or writeup that cemented this hypothesis for you?

                    JohnJ 1 Reply Last reply
                    0
                    • JohnJ John

                      GLP-1s have proven to me that the vast majority of overweight people are that way because a key part of their endocrine system was damaged by a viral infection - likely a variant of adenovirus that has been plaguing humanity since the late 70s.

                      SARS2, by being so flagrant about its damage to the body's systems and rewriting of genes, has helped reveal that a significant number of long-term illnesses and cancers are literally *caused* by viral infections.

                      The obesity crisis is no different.

                      1/

                      salS This user is from outside of this forum
                      salS This user is from outside of this forum
                      sal
                      wrote last edited by
                      #13
                      @johnzajac Have you looked at how much of the weight-to-mortality link is skewed by doctor discrimination as well, as in doctors literally denying fat patients the tests they would offer a thin patient with identical symptoms, and treatments they would offer a thin patient with an identical diagnosis?

                      It's also worth narrowing down what the more-common associated diseases are, like high cholesterol or elevated blood pressure, and it turns out that weight loss can't be counted on to actually resolve either of these.
                      JohnJ 1 Reply Last reply
                      0
                      • TaelT Tael

                        @johnzajac That's just what I read on Wikipedia. Is there a particular study or writeup that cemented this hypothesis for you?

                        JohnJ This user is from outside of this forum
                        JohnJ This user is from outside of this forum
                        John
                        wrote last edited by
                        #14

                        @tael

                        Like I said I'm just a person on meds with a theory and just enough knowledge to be dangerous to myself and others

                        That's why I always say I'm an opera singer 😂

                        And why I never offer advice, just observations and opinions.

                        If I have a study supporting my position (like I do when I post COVID stat stuff) I usually post it

                        Posted a Nature study on adenovirus higher in the thread

                        1 Reply Last reply
                        0
                        • salS sal
                          @johnzajac Have you looked at how much of the weight-to-mortality link is skewed by doctor discrimination as well, as in doctors literally denying fat patients the tests they would offer a thin patient with identical symptoms, and treatments they would offer a thin patient with an identical diagnosis?

                          It's also worth narrowing down what the more-common associated diseases are, like high cholesterol or elevated blood pressure, and it turns out that weight loss can't be counted on to actually resolve either of these.
                          JohnJ This user is from outside of this forum
                          JohnJ This user is from outside of this forum
                          John
                          wrote last edited by
                          #15

                          @sal

                          I've lived it lol

                          Like I wrote, I'm not saying folks have to lose weight, just that there's evidence that the obesity epidemic is real and caused at least in part by a viral pandemic

                          1 Reply Last reply
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