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  3. One of my chemistry students made drugs.

One of my chemistry students made drugs.

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  • Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
    Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
    Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿
    wrote last edited by
    #1

    One of my chemistry students made drugs. Aspirin, in this case. They confirmed they'd nailed it with a very accurate melting point measurement and then some thin layer chromatography. Yield was a little low, but hey, first go using high school kit. I made them a little souvenir, 0.06g of it in a tiny handmade phial.

    Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ Strider LongshanksS 2 Replies Last reply
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    • Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿

      One of my chemistry students made drugs. Aspirin, in this case. They confirmed they'd nailed it with a very accurate melting point measurement and then some thin layer chromatography. Yield was a little low, but hey, first go using high school kit. I made them a little souvenir, 0.06g of it in a tiny handmade phial.

      Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
      Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
      Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿
      wrote last edited by
      #2

      That's just under a quarter of a standard tablet, which are normally bulked out with lactose and chalk, student considered that in the TLC/chromatography tests. And as I'm not *giving* them a drug, merely packaging one they made themself, and they wrote a detailed risk assessment for the experiment including the end product, fair enough I think 😉

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      • Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿

        One of my chemistry students made drugs. Aspirin, in this case. They confirmed they'd nailed it with a very accurate melting point measurement and then some thin layer chromatography. Yield was a little low, but hey, first go using high school kit. I made them a little souvenir, 0.06g of it in a tiny handmade phial.

        Strider LongshanksS This user is from outside of this forum
        Strider LongshanksS This user is from outside of this forum
        Strider Longshanks
        wrote last edited by
        #3

        @_thegeoff This was one of my O-level projects back in the day - good to see it still has traction! 👍

        Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ 1 Reply Last reply
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        • Strider LongshanksS Strider Longshanks

          @_thegeoff This was one of my O-level projects back in the day - good to see it still has traction! 👍

          Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
          Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
          Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿
          wrote last edited by
          #4

          @StriderLongshanks Not part of the curriculum, but one of the suggested Advanced Higher(~17/18yo) projects. Second time in 6 years I've seen it done, both times good students who got good results and asked me interesting questions. (I'm very much a uni technician at this point, we can discuss the practicalities of an expriment, but I can't guide them into how they do the project, makes for careful conversation at times!)

          Strider LongshanksS 1 Reply Last reply
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          • Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿

            @StriderLongshanks Not part of the curriculum, but one of the suggested Advanced Higher(~17/18yo) projects. Second time in 6 years I've seen it done, both times good students who got good results and asked me interesting questions. (I'm very much a uni technician at this point, we can discuss the practicalities of an expriment, but I can't guide them into how they do the project, makes for careful conversation at times!)

            Strider LongshanksS This user is from outside of this forum
            Strider LongshanksS This user is from outside of this forum
            Strider Longshanks
            wrote last edited by
            #5

            @_thegeoff I can imagine 😏 e.g. it would be helpful if you didn't cause an explosion in the lab with some highly flammable evaporative solvents or poison your other class members with escaped gases from the laminar flow cupboard. Then again, perhaps these things have become slightly more difficult if there are restrictions on the types of reagents you can use today in a minor's education setting? Health and safety, etc?

            Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ 1 Reply Last reply
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            • Strider LongshanksS Strider Longshanks

              @_thegeoff I can imagine 😏 e.g. it would be helpful if you didn't cause an explosion in the lab with some highly flammable evaporative solvents or poison your other class members with escaped gases from the laminar flow cupboard. Then again, perhaps these things have become slightly more difficult if there are restrictions on the types of reagents you can use today in a minor's education setting? Health and safety, etc?

              Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
              Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
              Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿
              wrote last edited by
              #6

              @StriderLongshanks Health and safety is a big one, as in they need to properly risk assess everything before I even give them reagents. They're almost always way too careful, which is good. Two interesting incidents in 6 years, both students saying "erm...can you double check this?", and both were right to do so. One with a sealed system that may have gone bang (safely, in a fume cupboard), the other nearly rediscovered nitrocellulose by the original accident.

              Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ 1 Reply Last reply
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              • Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿

                @StriderLongshanks Health and safety is a big one, as in they need to properly risk assess everything before I even give them reagents. They're almost always way too careful, which is good. Two interesting incidents in 6 years, both students saying "erm...can you double check this?", and both were right to do so. One with a sealed system that may have gone bang (safely, in a fume cupboard), the other nearly rediscovered nitrocellulose by the original accident.

                Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
                Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
                Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿
                wrote last edited by
                #7

                @StriderLongshanks We only let them play with the "fun stuff" if we're confident they have the understanding to do it safely, and the confidence to come to me or one of the teachers if they mess up. I applaud anyone coming to me with a spillage etc as being exactly the right thing to do.

                Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ 1 Reply Last reply
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                • Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿

                  @StriderLongshanks We only let them play with the "fun stuff" if we're confident they have the understanding to do it safely, and the confidence to come to me or one of the teachers if they mess up. I applaud anyone coming to me with a spillage etc as being exactly the right thing to do.

                  Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
                  Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
                  Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿
                  wrote last edited by
                  #8

                  @StriderLongshanks this is 16+, usually 17 or 18 year old students in this context, working in their own lab. Very different rules for <16s.

                  Strider LongshanksS 1 Reply Last reply
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                  • Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿

                    @StriderLongshanks this is 16+, usually 17 or 18 year old students in this context, working in their own lab. Very different rules for <16s.

                    Strider LongshanksS This user is from outside of this forum
                    Strider LongshanksS This user is from outside of this forum
                    Strider Longshanks
                    wrote last edited by
                    #9

                    @_thegeoff Still a good exercise though, I loved doing mine (had two different ones at the time, the 2nd being the extraction and quantification and differentiation of caffeine and theine), and learnt a lot from my setbacks too. Certainly confirmed my interest in it for further study, due in no small part to the teaching and support staff of the lab👍

                    Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ 1 Reply Last reply
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                    • Strider LongshanksS Strider Longshanks

                      @_thegeoff Still a good exercise though, I loved doing mine (had two different ones at the time, the 2nd being the extraction and quantification and differentiation of caffeine and theine), and learnt a lot from my setbacks too. Certainly confirmed my interest in it for further study, due in no small part to the teaching and support staff of the lab👍

                      Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
                      Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿_ This user is from outside of this forum
                      Geoff 🏴󠁧󠁢󠁳󠁣󠁴󠁿
                      wrote last edited by
                      #10

                      @StriderLongshanks Aww, shucks 😚

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