I don't normally get emotional about these things, but one thing Gnome did that negatively affected myself and others, I think unnecessarily, was not making GTK3 backwards compatible. That rendered a whole suite of very good audio plugin GUIs (Calf) obsolete. And I think the original developer has abandoned the project, so they may never get updated. (Not sure if I got all the details right there but that's the outcome.)
thezorse@hear-me.social
@thezorse@hear-me.social