An observational study of 184 women who underwent breast cancer surgery, half of whom had vitamin D deficiency, found that those with vitamin D deficiency experienced more post-operative pain and self-administered more pain medication.
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An observational study of 184 women who underwent breast cancer surgery, half of whom had vitamin D deficiency, found that those with vitamin D deficiency experienced more post-operative pain and self-administered more pain medication.
Summary: https://www.sciencedaily.com/releases/2026/05/260519224308.htm
Original paper: https://rapm.bmj.com/content/early/2026/05/04/rapm-2025-107495
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T #medicine shared this topic
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An observational study of 184 women who underwent breast cancer surgery, half of whom had vitamin D deficiency, found that those with vitamin D deficiency experienced more post-operative pain and self-administered more pain medication.
Summary: https://www.sciencedaily.com/releases/2026/05/260519224308.htm
Original paper: https://rapm.bmj.com/content/early/2026/05/04/rapm-2025-107495
Anecdotal: I have a number of things that cause long term, irreversible, chronic pain. Unfortunately, I live in a puritan culture that considers pain management to be coddling and unnecessary. My doctor of 30 years retired, and I’ve been unable to find any doctor who will write small dose opiates. (5mg hydrocodone 1x daily)
A physical therapist suggested adding D3 to my regime, and it has helped make things more bearable except during a flare, so that’s nice.
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Anecdotal: I have a number of things that cause long term, irreversible, chronic pain. Unfortunately, I live in a puritan culture that considers pain management to be coddling and unnecessary. My doctor of 30 years retired, and I’ve been unable to find any doctor who will write small dose opiates. (5mg hydrocodone 1x daily)
A physical therapist suggested adding D3 to my regime, and it has helped make things more bearable except during a flare, so that’s nice.
@MissConstrue @rdnielsen today is the first time I've read about vitamin d3 reducing chronic pain.
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@MissConstrue @rdnielsen today is the first time I've read about vitamin d3 reducing chronic pain.
Yeah, it was like finding out there’s a combination of acetaminophen and ibuprofen that triggers an opioid like response in your brain, re serotonin release in descending pathways.
A fixed combination, typically 1000 mg of acetaminophen and 400 mg of ibuprofen, is the formula suggested as a non-opioid alternative.
https://pubmed.ncbi.nlm.nih.gov/39068515/
Is it as efficacious as small dose opioids? anecdotally I’d say it’s close, but I worry about long term use re liver.
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