@ubuntourist Just MeI'm a little nervous about side effectsThere are roughly 3 billion basepairs in the human genome, and we know that maybe 10% are critical, in that an edit would have some effectso this base editor has to have an error rate of ~~ < 1 in 300 millionwhich is unheard of for a chemical reactionnot sure this is real or not, but this sort of problem has gotten a LOT Of discussion among scientists

@Netraven @ahimsa_pdx indeed. It's not a limitation of medicine per se. It doesn't have to be like this

As one theory goes, some wag noticed that the expression of a person whose facial muscles were paralyzed by a treatment with "busu" apparently resembled less than-appealing women he may have encountered; thus, the word "busu" eventually came to refer to people whose faces look like they were poisoned with monkshood, and then more generally to people with less-than-appealing facial appearance. (Relatedly, there is a kyogen play entitled "Busu", where monkshood is featured as a plot device. There are performances of it on YouTube, e.g. https://youtu.be/D-8cbbUPRNo)The closest analogue of this derogatory term to modern times would be "Botox face": both botulinum toxin and monkshood have paralyzing qualities, that one treated by any of those toxins in inappropriate dosages has an unnatural facial appearance, and is thus subject to mockery.(2/2)

Wasn't being a detached observer once a goal of the training of a physician? The adjective "clinical" means to be calm and analytical.